Computers Cure Cancer

Recent advances in sequencing technologies have led to increases in data generation rates that far outpace Moore’s law and current increases in storage capacity. Over the past few years, sequencers have gone from generating megabases of DNA sequence and megabytes of data per day to gigabases of sequence and terabytes of data per day.

While this level of data generation and requisite analysis has severely taxed every aspect of our hardware and software infrastructure, it has also enabled the near routine sequencing of human genomes. This has allowed the application of whole-genome sequencing to understanding diseases of the genome such as cancer.

This presentation will provide an insiders look at The Genome Center's high-through sequence generation and analysis facility and its application to cancer genomes. Specifically, the enterprise IT infrastructure and software architecture will be detailed. The software architecture section will include a description of our freely-available, advanced, enterprise ORM and workflow systems.

Here are slides from the talk.